Formulation of mucoadhesive microspheres of rosiglitazone maleate and its in vitro evaluation using ionotropic gelation technique
نویسندگان
چکیده
منابع مشابه
Formulation of mucoadhesive microspheres of rosiglitazone maleate and its in vitro evaluation using ionotropic gelation technique
Aim: The objective of the present study is to design and evaluate mucoadhesive microspheres for oral controlled release. Materials and Method: Rosiglitazone maleate microspheres with a coat consisting of alginate and a mucoadhesive polymer sodium carboxymethylcellulose, carbopol 934P and hydroxypropylmethylcellulose were prepared by an orifice-ionic gelation process. The microspheres were evalu...
متن کاملFormulation of Ibuprofen Beads by Ionotropic Gelation
Microencapsulation has become a common technique in the production of controlled release dosage forms. Many results have been reported, concerning the use of alginate beads as controlled release drug formulations. Alginate has a unique gel-forming property in the presence of multivalent cations, in an aqueous medium. Ibuprofen is an excellent analgesic and antipyretic, non-steroidal anti-inflam...
متن کاملFormulation and evaluation of captropril microspheres by ionic gelation technique
The development of oral sustained or controlled release dosage form of captopril has been an interested topic of research for a long period of time. Difficulties encountered on the fact that the drug is freely water soluble. Such drug is difficult to be delivered orally in a sustained or controlled release manner and, Due to its effectiveness and intensive use as a drug of choice in the treatme...
متن کاملFormulation and In Vitro Evaluation of Acyclovir Mucoadhesive Microspheres for Intravaginal Application
The purpose of the research was to formulate microspheres of acyclovir (ACV) using mucoadhesive polymers, sodium alginate and chitosan. Calcium chloride was used as the ionotropic gelling agent. Sodium alginate was crosslinked by calcium chloride leading to a slower release of the drug. Chitosan which is a cationic polymer interacted with sodium alginate, an anionic polymer, to form an interpol...
متن کاملFormulation of Ibuprofen Beads by Ionotropic Gelation
Microencapsulation has become a common technique in the production of controlled release dosage forms. Many results have been reported, concerning the use of alginate beads as controlled release drug formulations. Alginate has a unique gel-forming property in the presence of multivalent cations, in an aqueous medium. Ibuprofen is an excellent analgesic and antipyretic, non-steroidal anti-inflam...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Ars Pharmaceutica (Internet)
سال: 2015
ISSN: 2340-9894
DOI: 10.4321/s2340-98942015000200004